Follistatin Antikörper (C-Term)
Kurzübersicht für Follistatin Antikörper (C-Term) (ABIN2775337)
Target
Alle Follistatin (FST) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- SLCDELCPDS KSDEPVCASD NATYASECAM KEAACSSGVL LEVKHSGSCN
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against FST. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human FST
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 317 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Follistatin (FST)
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Andere Bezeichnung
- FST
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Hintergrund
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Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
Alias Symbols: FS
Protein Interaction Partner: INHBA, BMPR2, BMPR1A, C8orf33, TK1, MEST, INHBE, INHA, FN1, BMP5, TXN,
Protein Size: 317 -
Molekulargewicht
- 35 kDa
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Gen-ID
- 10468
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NCBI Accession
- NM_006350, NP_006341
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UniProt
- Q6FHE1
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Pathways
- Negative Regulation of Hormone Secretion
Target
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