Follistatin Antikörper (Middle Region)
Kurzübersicht für Follistatin Antikörper (Middle Region) (ABIN2775336)
Target
Alle Follistatin (FST) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- FST Antibody - middle region
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Sequenz
- ALLKARCKEQ PELEVQYQGR CKKTCRDVFC PGSSTCVVDQ TNNAYCVTCN
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Homologie
- Cow: 92%, Dog: 100%, Goat: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 77%
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Produktmerkmale
- This is a rabbit polyclonal antibody against FST. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FST
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42286-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Follistatin (FST)
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Andere Bezeichnung
- FST
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Hintergrund
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Background Information: Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
Gene Name: Follistatin
Alternative Symbols: FS
Protein Name: Follistatin
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Molekulargewicht
- 35kDa
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Gen-ID
- 10468
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NCBI Accession
- NP_006341
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UniProt
- B5BU94
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Pathways
- Negative Regulation of Hormone Secretion
Target
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