NNMT Antikörper (N-Term)

Produktnummer ABIN2775335

Der Kaninchen Polyklonal Anti-NNMT-Antikörper wurde für WB validiert. Er ist geeignet, NNMT in Proben von Human, Maus, Ratte, Hund und Schwein zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für NNMT Antikörper (N-Term) (ABIN2775335)

Target: NNMT (Nicotinamide N-Methyltransferase (NNMT))

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NNMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NNMT Antikörper

Bindungsspezifität: N-Term

Sequenz: MESGFTSKDT YLSHFNPRDY LEKYYKFGSR HSAESQILKH LLKNLFKIFC

Homologie: Dog: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NNMT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NNMT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Antigen size: 264 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NNMT Antikörper (ABIN2775335)

Ulanovskaya, Zuhl, Cravatt: "NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink." in: Nature chemical biology, Vol. 9, Issue 5, pp. 300-6, (2013) (PubMed).

Details zu NNMT

Target: NNMT (Nicotinamide N-Methyltransferase (NNMT))

Andere Bezeichnung: NNMT

Hintergrund: N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. NNMT responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
Protein Interaction Partner: UBC, BMF, ATF6, APP,
Protein Size: 264

Molekulargewicht: 29 kDa

Gen-ID: 4837

NCBI Accession: NM_006169, NP_006160

UniProt: P40261