EBI3 Antikörper (Middle Region)
Kurzübersicht für EBI3 Antikörper (Middle Region) (ABIN2775323)
Target
Alle EBI3 (IL-27b) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- TAVHPWGSSS SFVPFITEHI IKPDPPEGVR LSPLAERQLQ VQWEPPGSWP
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Homologie
- Dog: 91%, Guinea Pig: 93%, Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against EBI3. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human EBI3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 229 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
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Andere Bezeichnung
- EBI3
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Substanzklasse
- Viral Protein
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Hintergrund
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This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
Alias Symbols: IL27B, IL-27B
Protein Interaction Partner: SMAD3, IL27RA, MDFI, GOSR1, IL12A, CANX,
Protein Size: 229 -
Molekulargewicht
- 23 kDa
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Gen-ID
- 10148
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NCBI Accession
- NM_005755, NP_005746
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UniProt
- Q14213
Target
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