KRT16 Antikörper (Middle Region)

Produktnummer ABIN2775314

Produktdetails anti-KRT16 Antikörper

Target: KRT16 (Keratin 16 (KRT16))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KRT16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IAATIENAQP ILQIDNARLA ADDFRTKYEH ELALRQTVEA DVNGLRRVLD

Homologie: Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against KRT16. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KRT16

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 473 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-KRT16 Antikörper (ABIN2775314)

Furukawa, Abe, Wang, Oki, Uda, Tsuneda, Ito: "Fluorogenic probe triggered by reduction for nucleic acids sensing." in: Nucleic acids symposium series (2004), Issue 52, pp. 353-4, (2008) (PubMed).

Details zu KRT16

Target: KRT16 (Keratin 16 (KRT16))

Andere Bezeichnung: KRT16 (KRT16 Produkte)

Hintergrund: KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles.The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CK16, K16, K1CP, KRT16A, NEPPK, FNEPPK
Protein Interaction Partner: UBC, Cep290, Nphp1, Invs, IQCB1, ITGA4, FN1, APOA1, ALB, EIF4A3, HNRNPM, UBASH3B, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, CAND1, COPS5, CUL1, CUL2, CUL3, CUL4B, NEDD8, BANF1, TCHP,
Protein Size: 473

Molekulargewicht: 51 kDa

Gen-ID: 3868

NCBI Accession: NM_005557, NP_005548

UniProt: P08779