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CES2 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-CES2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, CES2 in Proben von Human, Maus, Ratte, Hund und Meerschweinchen zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2775271

Kurzübersicht für CES2 Antikörper (C-Term) (ABIN2775271)

Target

Alle CES2 Antikörper anzeigen
CES2 (Carboxylesterase 2 (CES2))

Reaktivität

Human, Maus, Ratte, Hund, Meerschweinchen

Wirt

  • 33
  • 7
  • 3
  • 1
Kaninchen

Klonalität

  • 40
  • 4
Polyklonal

Konjugat

  • 32
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CES2 Antikörper ist unkonjugiert

Applikation

  • 37
  • 20
  • 19
  • 8
  • 7
  • 7
  • 6
  • 6
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    HWPLFDQEEQ YLQLNLQPAV GRALKAHRLQ FWKKALPQKI QELEEPEERH

    Homologie

    Dog: 83%, Guinea Pig: 83%, Human: 100%, Mouse: 83%, Rat: 83%

    Produktmerkmale

    This is a rabbit polyclonal antibody against CES2. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human CES2
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 623 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Target

    CES2 (Carboxylesterase 2 (CES2))

    Andere Bezeichnung

    CES2

    Hintergrund

    Carboxylesterase 2 is a member of a large multigene family. The enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system.Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: CE-2, iCE, PCE-2, CES2A1
    Protein Size: 623

    Molekulargewicht

    69 kDa

    Gen-ID

    8824

    NCBI Accession

    NM_003869, NP_003860

    UniProt

    O00748
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