DNA Helicase B Antikörper (N-Term)
Kurzübersicht für DNA Helicase B Antikörper (N-Term) (ABIN2775262)
Target
Alle DNA Helicase B (HELB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- FGRFPITGAW WRVKVQVKPV VGSRSYQYQV QGFPSYFLQS DMSPPNQKHI
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Homologie
- Cow: 86%, Guinea Pig: 79%, Human: 100%, Pig: 86%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against HELB. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HELB
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 1087 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication." in: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40853-61, (2002) (PubMed).
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: "A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication." in: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40853-61, (2002) (PubMed).
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- DNA Helicase B (HELB)
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Andere Bezeichnung
- HELB
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Hintergrund
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The protein encoded by this gene is a DNA helicase. A dominant-negative mutant of this protein blocks chromosomal DNA replication and suggests that its function is required for S phase entry.
Alias Symbols: hDHB
Protein Interaction Partner: UBC, PMS1, POLA2, POLA1, RPA1,
Protein Size: 1087 -
Molekulargewicht
- 120 kDa
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Gen-ID
- 92797
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NCBI Accession
- NM_033647, NP_387467
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UniProt
- Q8NG08
Target
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