DHX58 Antikörper (N-Term)

Produktnummer ABIN2775259

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DHX58 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Meerschweinchen, Pferd, Rind (Kuh), Hund und Kaninchen.

Kurzübersicht für DHX58 Antikörper (N-Term) (ABIN2775259)

Target: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Pferd, Rind (Kuh), Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX58 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DHX58 Antikörper

Bindungsspezifität: N-Term

Sequenz: AYVAKRHLET VDGAKVVVLV NRVHLVTQHG EEFRRMLDGR WTVTTLSGDM

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 91%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DHX58. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX58

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 678 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DHX58

Target: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Andere Bezeichnung: DHX58

Hintergrund: DHX58 is the negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA. Bin
Alias Symbols: D11LGP2, D11lgp2e, LGP2
Protein Interaction Partner: USP21, APP, UBD, NKRF, CDKN2AIP, AGO2, STAU2, DICER1, DHX30, XRN2, STAU1, EIF2AK2, EIF6, AP2B1,
Protein Size: 678

Molekulargewicht: 76 kDa

Gen-ID: 79132

NCBI Accession: NM_024119, NP_077024

UniProt: Q96C10