DHX8 Antikörper (N-Term)

Produktnummer ABIN2775203

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DHX8 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd und Meerschweinchen.

Kurzübersicht für DHX8 Antikörper (N-Term) (ABIN2775203)

Target: DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8 (DHX8))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DHX8 Antikörper

Bindungsspezifität: N-Term

Sequenz: VKNGAEFTDS LISNLLRLIQ TMRPPAKPST SKDPVVKPKT EKEKLKELFP

Homologie: Cow: 100%, Dog: 88%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DHX8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1220 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DHX8

Target: DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8 (DHX8))

Andere Bezeichnung: DHX8

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Alias Symbols: DDX8, HRH1, PRP22, PRPF22
Protein Interaction Partner: NUDCD1, UBC, LIN28A, XRN2, SRPK2, SRPK1, BAG3, PRPF38A, NKAP, ISY1, PRPF40A, ZCCHC10, RBMX2, SAP30BP, CHERP, RBM7, THOC1, MFAP1, DHX8, NOTCH1, KANSL1, PHF5A, MYPN, POLR1B, CRNKL1, TAF9, SMAD3, SMAD2, CAND1, CUL3, SIRT7, USP12,
Protein Size: 1220

Molekulargewicht: 139 kDa

Gen-ID: 1659

NCBI Accession: NM_004941, NP_004932

UniProt: Q14562