BAT1 Antikörper (C-Term)

Produktnummer ABIN2775195

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BAT1 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Hund, Maus, Rind (Kuh), Ziege, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.

Kurzübersicht für BAT1 Antikörper (C-Term) (ABIN2775195)

Target: BAT1 (DDX39) (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39))

Reaktivität: Human, Ratte, Hund, Maus, Rind (Kuh), Ziege, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BAT1 Antikörper

Bindungsspezifität: C-Term

Sequenz: YDMPEDSDTY LHRVARAGRF GTKGLAITFV SDENDAKILN DVQDRFEVNI

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against BAT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BAT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 428 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-BAT1 Antikörper (ABIN2775195)

Bouley, Pionneau, Varinot, Biard, Genestie, Antoine, Coulet, Stern, Stoppa-Lyonnet, Soubrier: "Proteomic analysis of BRCA1-depleted cell line reveals a putative role for replication protein A2 up-regulation in BRCA1 breast tumor development." in: Proteomics. Clinical applications, Vol. 4, Issue 5, pp. 489-98, (2010) (PubMed).

Details zu BAT1

Target: BAT1 (DDX39) (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39))

Andere Bezeichnung: BAT1

Hintergrund: BAT1 is a member of the DEAD protein family of ATP-dependent RNA helicases. Members of this family are involved in a number of cellular functions including initiation of translation, RNA splicing, and ribosome assembly. A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This protein is a negative regulator of inflammation. It is also thought to be a translation initiation factor. This gene is a strong candidate gene for rheumatoid arthritis. There are multiple alternatively spliced transcript variants known for this gene but only two have been fully described. Both of these variants encode the same isoform. This gene has been found to have multiple polyadenylation sites.
Alias Symbols: BAT1, UAP56, D6S81E
Protein Interaction Partner: THOC3, THOC2, ALYREF, NCBP1, STAU1, SHFM1, UBC, MDM2, WWOX, SUZ12, EED, RNF2, BMI1, RBBP4, C12orf10, NDRG1, HSPD1, GSR, SRPK2, UBD, VCAM1, ITGA4, IL7R, FN1, ATF2, BARD1, WIBG, MAGOHB, WDR74, VPS33B, LSM4, THOC1, RBM8A, DHX38, TXNL1, UBE3A, RPS7, EIF4A2, R
Protein Size: 428

Molekulargewicht: 47 kDa

Gen-ID: 7919

NCBI Accession: NM_080598, NP_542165

UniProt: Q13838

Pathways: Ribonucleoprotein Complex Subunit Organization