DHX9 Antikörper (N-Term)

Produktnummer ABIN2775181

Der Kaninchen Polyklonal Anti-DHX9-Antikörper wurde für WB und IHC validiert. Er ist geeignet, DHX9 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen und Schwein zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für DHX9 Antikörper (N-Term) (ABIN2775181)

Target: DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-DHX9 Antikörper

Bindungsspezifität: N-Term

Sequenz: GLHGNWTLEN AKARLNQYFQ KEKIQGEYKY TQVGPDHNRS FIAEMTIYIK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DHX9. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX9

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1279 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DHX9 Antikörper (ABIN2775181)

Kawai, Amano: "BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex." in: The Journal of cell biology, Vol. 197, Issue 2, pp. 201-8, (2012) (PubMed).

Details zu DHX9

Target: DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Andere Bezeichnung: DHX9

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DHX9 is a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression. It contains 2 copies of a double-stranded RNA-binding domain, a DEXH core domain and an RGG box. The RNA-binding domains and RGG box influence and regulate RNA helicase activity.
Alias Symbols: DDX9, LKP, NDH II, NDHII, RHA, NDH2
Protein Interaction Partner: UBC, PA2G4, FBXW11, AURKA, SUMO2, SUMO3, MDM2, CEP250, SART3, STAU1, IVNS1ABP, EIF2AK2, LGR4, SUMO1, WWOX, RPA3, RPA2, RPA1, SUZ12, EED, EZH2, RNF2, rev, DDX1, APBB1, ABCF1, FLII, PRPF40A, C14orf166, RTCB, RPL26L1, NELFB, HNRNPA0, IGF2BP3, LRRFIP1, MAP7,
Protein Size: 1279

Molekulargewicht: 141 kDa

Gen-ID: 1660

NCBI Accession: NM_001357, NP_001348

UniProt: Q08211