AKAP10 Antikörper (Middle Region)

Produktnummer ABIN2775175

Der Kaninchen Polyklonal Anti-AKAP10-Antikörper wurde für WB validiert. Er ist geeignet, AKAP10 in Proben von Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Pferd, Schwein und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für AKAP10 Antikörper (Middle Region) (ABIN2775175)

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Pferd, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AKAP10 Antikörper

Bindungsspezifität: Middle Region

Sequenz: ESLYQRTYAG KMTFGRVSDL GQFIRESEPE PDVRKSKGSM FSQAMKKWVQ

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against AKAP10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AKAP10

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 662 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AKAP10

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Andere Bezeichnung: AKAP10

Hintergrund: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
Alias Symbols: D-AKAP2, MGC9414, PRKA10
Protein Interaction Partner: COG3, DCTN4, MYH9, PRKAR1A, HAX1, SLC9A3R1, PDZK1, PRKAR2B, PRKAR2A,
Protein Size: 662

Molekulargewicht: 71 kDa

Gen-ID: 11216

NCBI Accession: NM_007202, NP_009133

UniProt: O43572

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling