SP110 Antikörper (C-Term)

Produktnummer ABIN2775054

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SP110 in WB. Er zeigt eine Reaktivität gegenüber Human, Hund und Schwein.

Kurzübersicht für SP110 Antikörper (C-Term) (ABIN2775054)

Target: SP110 (SP110 Nuclear Body Protein (SP110))

Reaktivität: Human, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SP110 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SP110 Antikörper

Bindungsspezifität: C-Term

Sequenz: LITEMYTVAW FVRDMRLMFR NHKTFYKASD FGQVGLDLEA EFEKDLKDVL

Homologie: Dog: 79%, Human: 100%, Pig: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SP110. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SP110

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 713 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SP110

Target: SP110 (SP110 Nuclear Body Protein (SP110))

Andere Bezeichnung: SP110

Hintergrund: The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. SP110 is a member of the SP100/SP140 family of nuclear body proteins and is a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation.The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
Alias Symbols: FLJ22835, IFI41, IFI75, VODI, IPR1
Protein Interaction Partner: UBC, CEBPA, OSGEP, TSC22D1, TTR, TK1, SMN1, CDKN1A, ANXA7, ZSCAN9, NAP1L2, RUNX3, NDUFV2,
Protein Size: 713

Molekulargewicht: 81 kDa

Gen-ID: 3431

NCBI Accession: NM_080424, NP_536349

UniProt: Q9HB58