DUX4 Antikörper (N-Term)

Produktnummer ABIN2775040

Der Kaninchen Polyklonal anti-DUX4 Antikörper (ABIN2775040) detektiert spezifisch DUX4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DUX4 Antikörper (N-Term) (ABIN2775040)

Target: DUX4 (Double Homeobox 4 (DUX4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DUX4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: DUX4 Antibody - N-terminal region

Sequenz: TRGAEGTLGG RQGGREAGRN GGRDRATQGL GAGPREPGTD GGRKAGRKSG

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DUX4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human DUX4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36096-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DUX4

Target: DUX4 (Double Homeobox 4 (DUX4))

Andere Bezeichnung: DUX4

Hintergrund:

Background Information: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length, a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes, the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1, GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants.

Gene Name: double homeobox 4

Alternative Symbols: DUX4L

Protein Name: double homeobox protein 4

Molekulargewicht: 93kDa

Gen-ID: 100288687

NCBI Accession: NP_001280727

UniProt: Q9UBX2