HOXB8 Antikörper (Middle Region)

Produktnummer ABIN2774996

Dieses Anti-HOXB8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HOXB8 in WB. Geeignet für Human, Maus, Ratte, Hund und Schwein.

Kurzübersicht für HOXB8 Antikörper (Middle Region) (ABIN2774996)

Target: HOXB8 (Homeobox B8 (HOXB8))

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXB8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HOXB8 Antikörper

Bindungsspezifität: Middle Region

Sequenz: FQNRRMKWKK ENNKDKFPSS KCEQEELEKQ KLERAPEAAD EGDAQKGDKK

Homologie: Dog: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXB8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXB8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 243 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HOXB8

Target: HOXB8 (Homeobox B8 (HOXB8))

Andere Bezeichnung: HOXB8

Hintergrund: HOXB8 belongs to the Antp homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. This gene is included in a cluster of homeobox B genes located on chromosome 17. The protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
Alias Symbols: HOX2, HOX2D, Hox-2.4
Protein Interaction Partner: PBX3, PBX2, PBX1, MEIS1,
Protein Size: 243

Molekulargewicht: 27 kDa

Gen-ID: 3218

NCBI Accession: NM_024016, NP_076921

UniProt: P17481