RNF6 Antikörper (C-Term)

Produktnummer ABIN310423

Produktdetails anti-RNF6 Antikörper

Target: RNF6 (RING Finger Protein 6 (RNF6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VETGTLPILR LAHFFLLNES DDDDRIRGLT KEQIDNLSTR HYEHNSIDSE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 92%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against RNF6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 685 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RNF6

Target: RNF6 (RING Finger Protein 6 (RNF6))

Andere Bezeichnung: RNF6 (RNF6 Produkte)

Hintergrund: RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Alias Symbols: DKFZp686P0776
Protein Interaction Partner: UBE2D1, AR, LDB1, UBC, tat, UBE2H,
Protein Size: 685

Molekulargewicht: 78 kDa

Gen-ID: 6049

NCBI Accession: NM_005977, NP_005968

UniProt: Q9Y252

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size