RNF6 Antikörper (C-Term)

Produktnummer ABIN2774919

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RNF6 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für RNF6 Antikörper (C-Term) (ABIN2774919)

Target: RNF6 (RING Finger Protein 6 (RNF6))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RNF6 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: RNF6 Antibody - C-terminal region

Sequenz: VETGTLPILR LAHFFLLNES DDDDRIRGLT KEQIDNLSTR HYEHNSIDSE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 92%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against RNF6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110889

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RNF6

Target: RNF6 (RING Finger Protein 6 (RNF6))

Andere Bezeichnung: RNF6

Hintergrund:

Background Information: RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.

Gene Name: Ring finger protein (C3H2C3 type) 6

Alternative Symbols: DKFZp686P0776

Protein Name: E3 ubiquitin-protein ligase RNF6

Molekulargewicht: 78kDa

Gen-ID: 6049

NCBI Accession: NP_005968

UniProt: Q9Y252

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size