Annexin IV Antikörper (N-Term)

Produktnummer ABIN2774909

Der Kaninchen Polyklonal Anti-Annexin IV-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Annexin IV in Proben von Human, Ratte, Maus, Hund, Schwein, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd und Zebrafisch (Danio rerio) zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Annexin IV Antikörper (N-Term) (ABIN2774909)

Target: Annexin IV (ANXA4) (Annexin A4 (ANXA4))

Reaktivität: Human, Ratte, Maus, Hund, Schwein, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin IV Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Annexin IV Antikörper

Bindungsspezifität: N-Term

Sequenz: GLGTDEDAII SVLAYRNTAQ RQEIRTAYKS TIGRDLIDDL KSELSGNFEQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ANXA4. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 321 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Annexin IV Antikörper (ABIN2774909)

de la Cuesta, Alvarez-Llamas, Maroto, Donado, Zubiri, Posada, Padial, Pinto, Barderas, Vivanco: "A proteomic focus on the alterations occurring at the human atherosclerotic coronary intima." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 4, pp. M110.003517, (2011) (PubMed).

Staquicini, Cardó-Vila, Kolonin, Trepel, Edwards, Nunes, Sergeeva, Efstathiou, Sun, Almeida, Tu, Botz, Wallace, OConnell, Krajewski, Gershenwald, Molldrem, Flamm, Koivunen, Pentz, Dias-Neto, Setubal et al.: "Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 46, pp. 18637-42, (2011) (PubMed).

Details zu Annexin IV

Target: Annexin IV (ANXA4) (Annexin A4 (ANXA4))

Andere Bezeichnung: ANXA4

Hintergrund: Annexin A4 (ANXA4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANXA4 has 45 to 59 % identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANXA4 is almost exclusively expressed in epithelial cells.
Alias Symbols: ANX4, PIG28, ZAP36
Protein Interaction Partner: PADI4, UBC, EZH2, DNAJB11, MPST, ANXA7, ANXA3, ANXA1, TINF2, POT1, SUMO2, NMT2, SMPD1, Cdk1, UCHL5, H2AFX, NFKB1, GP2,
Protein Size: 321

Molekulargewicht: 35 kDa

Gen-ID: 307

NCBI Accession: NM_001153, NP_001144

UniProt: Q6LES2