IBSP Antikörper (N-Term)

Produktnummer ABIN2774907

Der Kaninchen Polyklonal anti-IBSP Antikörper (ABIN2774907) detektiert spezifisch IBSP in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Hund.

Kurzübersicht für IBSP Antikörper (N-Term) (ABIN2774907)

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IBSP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IBSP Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: IBSP Antibody - N-terminal region

Sequenz: SATTLGYGED ATPGTGYTGL AAIQLPKKAG DITNKATKEK ESDEEEEEEE

Homologie: Dog: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IBSP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IBSP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36681-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IBSP

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Andere Bezeichnung: IBSP

Hintergrund:

Background Information: The protein encoded by the IBSP gene is a major structural protein of the bone matrix. It constitutes approximately 12 % of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Gene Name: Integrin-binding sialoprotein

Alternative Symbols: BSP, BNSP, SP-II, BSP-II

Protein Name: Bone sialoprotein 2

Molekulargewicht: 35kDa

Gen-ID: 3381

NCBI Accession: NP_004958

UniProt: P21815