IBSP Antikörper (N-Term)

Produktnummer ABIN2774907

Dieses Anti-IBSP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IBSP in WB. Geeignet für Human und Hund.

Kurzübersicht für IBSP Antikörper (N-Term) (ABIN2774907)

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IBSP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IBSP Antikörper

Bindungsspezifität: N-Term

Sequenz: SATTLGYGED ATPGTGYTGL AAIQLPKKAG DITNKATKEK ESDEEEEEEE

Homologie: Dog: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IBSP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IBSP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 317 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IBSP

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Andere Bezeichnung: IBSP

Hintergrund: The protein encoded by the IBSP gene is a major structural protein of the bone matrix. It constitutes approximately 12 % of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
Alias Symbols: BSP, BNSP, SP-II, BSP-II
Protein Size: 317

Molekulargewicht: 35 kDa

Gen-ID: 3381

NCBI Accession: NM_004967, NP_004958

UniProt: P21815