MCM8 Antikörper (N-Term)

Produktnummer ABIN2774899

Der Kaninchen Polyklonal anti-MCM8 Antikörper wird verwendet zum Nachweis von MCM8 in Proben von Human, Ratte, Maus, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Hund und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für MCM8 Antikörper (N-Term) (ABIN2774899)

Target: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MCM8 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MCM8 Antibody - N-terminal region

Sequenz: ELRDAPEKTL ACMGLAIHQV LTKDLERHAA ELQAQEGLSN DGETMVNVPH

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 91%, Rat: 100%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against MCM8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MCM8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105452

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MCM8

Target: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Andere Bezeichnung: MCM8

Hintergrund:

Background Information: MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene Name: Minichromosome maintenance complex component 8

Alternative Symbols: POF10, C20orf154, dJ967N21.5

Protein Name: DNA helicase MCM8

Molekulargewicht: 92kDa

Gen-ID: 84515

NCBI Accession: NP_115874

UniProt: Q9UJA3

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA