GJB4 Antikörper (Middle Region)

Produktnummer ABIN2774873

Der Kaninchen Polyklonal anti-GJB4 Antikörper wird verwendet zum Nachweis von GJB4 in Proben von Human, Maus, Ratte, Pferd, Rind (Kuh) und Hund. Er wurde validiert für WB.

Kurzübersicht für GJB4 Antikörper (Middle Region) (ABIN2774873)

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GJB4 Antikörper

Bindungsspezifität: Middle Region

Sequenz: CPSLLVVMHV AYREERERKH HLKHGPNAPS LYDNLSKKRG GLWWTYLLSL

Homologie: Cow: 92%, Dog: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against GJB4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GJB4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 266 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GJB4

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Andere Bezeichnung: GJB4

Hintergrund: Connexins are homologous four-transmembrane-domain proteins and major components of gap junctions. The GJB4 gene encodes connexin 30.3 (Cx30.3) A mutation in connexin 30.3 is causally involved in erythrokeratodermia variabilis (EKV), a mostly autosomal dominant disorder of keratinization.
Alias Symbols: EKV, CX30.3
Protein Interaction Partner: UBC,
Protein Size: 266

Molekulargewicht: 29 kDa

Gen-ID: 127534

NCBI Accession: NM_153212, NP_694944

UniProt: Q9NTQ9