GJB4 Antikörper (Middle Region)

Produktnummer ABIN2774873

Produktdetails anti-GJB4 Antikörper

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CPSLLVVMHV AYREERERKH HLKHGPNAPS LYDNLSKKRG GLWWTYLLSL

Homologie: Cow: 92%, Dog: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against GJB4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GJB4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 266 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GJB4

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Andere Bezeichnung: GJB4 (GJB4 Produkte)

Hintergrund: Connexins are homologous four-transmembrane-domain proteins and major components of gap junctions. The GJB4 gene encodes connexin 30.3 (Cx30.3) A mutation in connexin 30.3 is causally involved in erythrokeratodermia variabilis (EKV), a mostly autosomal dominant disorder of keratinization.
Alias Symbols: EKV, CX30.3
Protein Interaction Partner: UBC,
Protein Size: 266

Molekulargewicht: 29 kDa

Gen-ID: 127534

NCBI Accession: NM_153212, NP_694944

UniProt: Q9NTQ9