GJC2 Antikörper (Middle Region)
Kurzübersicht für GJC2 Antikörper (Middle Region) (ABIN2774865)
Target
Alle GJC2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- GJC2 Antibody - middle region
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Sequenz
- APASRTGSAT SAGTVGEQGR PGTHERPGAK PRAGSEKGSA SSRDGKTTVW
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Homologie
- Human: 100%, Rabbit: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against GJC2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GJC2
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36621-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))
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Andere Bezeichnung
- GJC2
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Hintergrund
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Background Information: GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
Gene Name: Gap junction protein, gamma 2, 47 kDa
Alternative Symbols: Cx47, HLD2, GJA12, SPG44, CX46.6, LMPH1C, LMPHM3, PMLDAR
Protein Name: Gap junction gamma-2 protein
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Molekulargewicht
- 47kDa
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Gen-ID
- 57165
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NCBI Accession
- NP_065168
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UniProt
- Q5T442
Target
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