ANXA6 Antikörper (N-Term)
Kurzübersicht für ANXA6 Antikörper (N-Term) (ABIN2774842)
Target
Alle ANXA6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- ALYTAMKGFG SDKEAILDII TSRSNRQRQE VCQSYKSLYG KDLIADLKYE
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Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 85%, Rat: 93%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ANXA6. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA6
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 673 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ANXA6 (Annexin A6 (ANXA6))
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Andere Bezeichnung
- ANXA6
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Hintergrund
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Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
Alias Symbols: ANX6, CBP68
Protein Interaction Partner: UBC, MDM2, THOP1, PLS3, MTAP, IDH1, HPRT1, GOT1, ADSS, POLE3, NAMPT, UBE2H, ATP4A, METTL18, MLH1, SNCA, CUL5, SIRT7, PRKCA, TJP1, CD4, H2AFX, CDC73, TPD52, S100B, S100A1, RASA1, CR2, A2M, tax,
Protein Size: 673 -
Molekulargewicht
- 74 kDa
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Gen-ID
- 309
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NCBI Accession
- NM_001155, NP_001146
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UniProt
- P08133
Target
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