Annexin a1 Antikörper (N-Term)

Produktnummer ABIN2774833

Dieses Anti-Annexin a1-Antikörper ist ein Rabbit Polyclonal-Antikörper zur Detektion von Annexin a1 in WB, IHC. Geeignet für Human, Mouse, Rat, Guinea Pig, Dog, Cow. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Annexin a1 Antikörper (N-Term) (ABIN2774833)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin a1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Annexin a1 Antikörper

Bindungsspezifität: N-Term

Sequenz: WFIENEEQEY VQTVKSSKGG PGSAVSPYPT FNPSSDVAAL HKAIMVKGVD

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 83%, Rat: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against ANXA1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 346 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Annexin a1 Antikörper (ABIN2774833)

Ishida, Yamasaki, Yukizaki, Nishiyama, Tsubouchi, Okayama, Kataoka et al.: "Carnosol, rosemary ingredient, induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion: proteomic approach using fluorescent two-dimensional differential gel ..." in: Human cell, Vol. 27, Issue 2, pp. 68-77, (2014) (PubMed).

Nordon, Hinchliffe, Malkawi, Pirianov, Torsney, Loftus, Cockerill, Thompson: "Comparative proteomics reveals a systemic vulnerability in the vasculature of patients with abdominal aortic aneurysms." in: Journal of vascular surgery, Vol. 54, Issue 4, pp. 1100-1108.e6, (2011) (PubMed).

Details zu Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: ANXA1

Hintergrund: ANXA1 encodes a protein that belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
Alias Symbols: ANX1, LPC1
Protein Interaction Partner: UBC, MEIS2, SUMO2, SUMO3, WWOX, ZBTB1, HECW2, YWHAQ, ATP4A, UBD, BAG3, HMGA1, VCAM1, ITGA4, FN1, ATF2, ANXA4, RIPK1, IKBKG, RELA, CUL5, CDK2, SIRT7, ANXA5, ANXA1, KLHL23, LRIF1, OTUB1, C1orf123, CSAD, C14orf1, FAF1, COPS6, CCT7, KMT2B, UNC119, SUMO1, UBE2
Protein Size: 346

Molekulargewicht: 38 kDa

Gen-ID: 301

NCBI Accession: NM_000700, NP_000691

UniProt: P04083

Pathways: Hormone Transport