MARCH5 Antikörper (C-Term)

Produktnummer ABIN2774747

Produktdetails anti-MARCH5 Antikörper

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VNSNLQRTIL GGIAFVAIKG AFKVYFKQQQ YLRQAHRKIL NYPEQEEA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against 39877. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MARCH5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 278 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MARCH5

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Andere Bezeichnung: MARCH5 (MARCH5 Produkte)

Synonyme: march5 antikoerper, MARCH5 antikoerper, mitol antikoerper, rnf153 antikoerper, march-v antikoerper, zgc:162966 antikoerper, MARCH-V antikoerper, Mar-05 antikoerper, MITOL antikoerper, RNF153 antikoerper, 1810015H18Rik antikoerper, 2310008I22Rik antikoerper, 2700055A20Rik antikoerper, 5730499H23Rik antikoerper, E130202O05Rik antikoerper, Marchv antikoerper, Rnf153 antikoerper, membrane-associated ring finger (C3HC4) 5 antikoerper, membrane associated ring-CH-type finger 5 antikoerper, membrane associated ring-CH-type finger 5 L homeolog antikoerper, march5 antikoerper, MARCH5 antikoerper, march5.L antikoerper, March5 antikoerper

Hintergrund: MARCH5 is an ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2) and DRP1 (DNM1L).MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2, MIM 608507) and DRP1 (DNM1L, MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1502 AK000452.1 3-1504 1503-1863 BC015480.1 1463-1823 1864-1901 BE393612.1 438-475 1902-3713 BC015480.1 1852-3663 3714-3941 BC015480.1 3669-3896
Alias Symbols: FLJ20445, MARCH-V, MITOL, RNF153
Protein Interaction Partner: FATE1, UBE2W, UBC, DNM1L, MFN2, UBE2E1, FIS1, UBE2E3, MFN1, PARK2, MARCH5, CCNB1, UBE2D3, UBE2D2, UBE2D1, MAP1B, KIAA0368, SOD1, MAVS, TANK, TRAF6, AKTIP, UBE2T, UBE2N, UBE2I, UTRN,
Protein Size: 278

Molekulargewicht: 31 kDa

Gen-ID: 54708

NCBI Accession: NM_017824, NP_060294

UniProt: Q9NX47