UBE2J1 Antikörper (N-Term)

Produktnummer ABIN2774737

Dieser Anti-UBE2J1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von UBE2J1 in WB und IHC. Geeignet für Human, Maus, Ratte, Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für UBE2J1 Antikörper (N-Term) (ABIN2774737)

Target: UBE2J1 (Ubiquitin-Conjugating Enzyme E2, J1, U (UBE2J1))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2J1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-UBE2J1 Antikörper

Bindungsspezifität: N-Term

Sequenz: METRYNLKSP AVKRLMKEAA ELKDPTDHYH AQPLEDNLFE WHFTVRGPPD

Homologie: Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against UBE2J1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2J1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 318 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBE2J1

Target: UBE2J1 (Ubiquitin-Conjugating Enzyme E2, J1, U (UBE2J1))

Andere Bezeichnung: UBE2J1

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2J1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.
Alias Symbols: CGI-76, HSPC153, HSPC205, HSU93243, MGC12555, NCUBE1, Ubc6p, UBC6, NCUBE-1
Protein Interaction Partner: UBC, UBA1, MAPKAPK2, OS9, RNF5, PARK2, DIO2, SOX6, TP53, AUP1, ASNA1, DERL3, DERL1, YOD1, DERL2, FAF2, VCP, SEL1L, ELAVL1, HLA-A, BIRC2, LRSAM1, TRIM63, SYVN1, TOPORS, PJA2, RNF2, TRIM27, BRCA1, BIRC3,
Protein Size: 318

Molekulargewicht: 35 kDa

Gen-ID: 51465

NCBI Accession: NM_016021, NP_057105

UniProt: Q9Y385