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RNF19A Antikörper (N-Term)

RNF19A Reaktivität: Human, Maus, Hund, Schwein, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2774733
  • Target Alle RNF19A Antikörper anzeigen
    RNF19A (Ring Finger Protein 19A (RNF19A))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Hund, Schwein, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Ratte
    Wirt
    • 48
    • 1
    • 1
    Kaninchen
    Klonalität
    • 49
    • 1
    Polyklonal
    Konjugat
    • 15
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF19A Antikörper ist unkonjugiert
    Applikation
    • 36
    • 26
    • 15
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    IFSTNTSSDN GLTSISKQIG DFIECPLCLL RHSKDRFPDI MTCHHRSCVD
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against RNF19A. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human RNF19A
    Top Product
    Discover our top product RNF19A Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 838 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RNF19A (Ring Finger Protein 19A (RNF19A))
    Andere Bezeichnung
    RNF19A (RNF19A Produkte)
    Synonyme
    RNF19 antikoerper, RNF19A antikoerper, AA032313 antikoerper, Dorfin antikoerper, Rnf19 antikoerper, UIP117 antikoerper, Ubce7ip2 antikoerper, XYbp antikoerper, ring finger protein 19A, RBR E3 ubiquitin protein ligase antikoerper, ring finger protein 19A antikoerper, RNF19A antikoerper, Rnf19a antikoerper
    Hintergrund
    RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
    Alias Symbols: DKFZp566B1346, DORFIN, RNF19
    Protein Interaction Partner: UBC, UBE2L3, Psmc3, ZAK, NUDT21, C11orf58, RPS6KA5, MAP3K7, ILK, SOD1, VCP, SNCAIP, CASR, UBE2E2, SUFU, TUBG2, UBE2L6, TUBG1,
    Protein Size: 838
    Molekulargewicht
    91 kDa
    Gen-ID
    25897
    NCBI Accession
    NM_015435, NP_056250
    UniProt
    Q9NV58
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