PDZRN3 Antikörper (N-Term)
Kurzübersicht für PDZRN3 Antikörper (N-Term) (ABIN2774727)
Target
Alle PDZRN3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- ELDRFDGDVD PDLKCALCHK VLEDPLTTPC GHVFCAGCVL PWVVQEGSCP
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Homologie
- Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 93%, Zebrafish: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PDZRN3. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDZRN3
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))
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Andere Bezeichnung
- PDZRN3
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Hintergrund
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PDZRN3 is a E3 ubiquitin-protein ligase. It plays an important role in regulating the surface level of MUSK on myotubes. It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. It might contribute to terminal myogenic differentiation.
Protein Interaction Partner: Dlg4, LNX2, LNX1, UBE2D2, MUSK, PDZRN3, BMPR2, EFNB2,
Protein Size: 729 -
Molekulargewicht
- 80 kDa
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Gen-ID
- 23024
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Pathways
- Skeletal Muscle Fiber Development
Target
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