PDZRN3 Antikörper (N-Term)

Produktnummer ABIN2774727

Produktdetails anti-PDZRN3 Antikörper

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZRN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ELDRFDGDVD PDLKCALCHK VLEDPLTTPC GHVFCAGCVL PWVVQEGSCP

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PDZRN3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDZRN3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDZRN3

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Andere Bezeichnung: PDZRN3 (PDZRN3 Produkte)

Synonyme: MGC80196 antikoerper, pdzrn3 antikoerper, LNX3 antikoerper, SEMACAP3 antikoerper, 1110020C07Rik antikoerper, AI429718 antikoerper, AL023082 antikoerper, Semcap3 antikoerper, PDZ domain containing ring finger 3 antikoerper, PDZ domain containing ring finger 3 L homeolog antikoerper, PDZ domain containing RING finger 3b antikoerper, E3 ubiquitin-protein ligase PDZRN3 antikoerper, PDZ domain containing RING finger 3 antikoerper, PDZRN3 antikoerper, pdzrn3.L antikoerper, pdzrn3b antikoerper, LOC100228989 antikoerper, pdzrn3 antikoerper, Pdzrn3 antikoerper

Hintergrund: PDZRN3 is a E3 ubiquitin-protein ligase. It plays an important role in regulating the surface level of MUSK on myotubes. It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. It might contribute to terminal myogenic differentiation.
Protein Interaction Partner: Dlg4, LNX2, LNX1, UBE2D2, MUSK, PDZRN3, BMPR2, EFNB2,
Protein Size: 729

Molekulargewicht: 80 kDa

Gen-ID: 23024

Pathways: Skeletal Muscle Fiber Development