FBXO21 Antikörper (N-Term)

Produktnummer ABIN2774725

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FBXO21 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Rind (Kuh) und Saccharomyces cerevisiae.

Kurzübersicht für FBXO21 Antikörper (N-Term) (ABIN2774725)

Target: FBXO21 (F-Box Protein 21 (FBXO21))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FBXO21 Antikörper

Bindungsspezifität: N-Term

Sequenz: KEQFRVRWPS LMKHYSPTDY VNWLEEYKVR QKAGLEARKI VASFSKRFFS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXO21. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO21

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 621 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXO21

Target: FBXO21 (F-Box Protein 21 (FBXO21))

Andere Bezeichnung: FBXO21

Hintergrund: FBXO21 contains 1 F-box domain. It is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: DKFZp434G058, FBX21, FLJ90233, KIAA0875, MGC26682
Protein Interaction Partner: TP53, CDKN1A, SUMO1, SMURF1, NEDD8, UBC, COPS5, COPS6, CUL1, ELAVL1, CNTNAP4, TERF2, TERF1,
Protein Size: 621

Molekulargewicht: 71 kDa

Gen-ID: 23014

NCBI Accession: NM_015002, NP_055817

UniProt: O94952