RNF40 Antikörper (C-Term)

Produktnummer ABIN2774720

Der Kaninchen Polyklonal Anti-RNF40-Antikörper wurde für WB und IHC validiert. Er ist geeignet, RNF40 in Proben von Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für RNF40 Antikörper (C-Term) (ABIN2774720)

Target: RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF40 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RNF40 Antikörper

Bindungsspezifität: C-Term

Sequenz: KLLREEKDEL GEQVLGLKSQ VDAQLLTVQK LEEKERALQG SLGGVEKELT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against RNF40. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF40

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1001 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RNF40

Target: RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))

Andere Bezeichnung: RNF40

Hintergrund: RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
Alias Symbols: BRE1B, DKFZp686K191, KIAA0661, MGC13051, RBP95, STARING
Protein Interaction Partner: UBE2A, UBC, SFR1, CCDC146, RNF20, AMOTL2, RNF40, UBE2I, UBE2B, MSL1, MSL2, PAF1, HIST2H2BE, CDK9, MDM2, USP15, HSP90AA1, NOTCH1, UBE2E1, RB1, ITSN1, CDC73, SUMO2, ATM, AR, TERF2, TERF1, WAC, ZNF451, TRIM51, UBE2L6, NCBP1, STX1A,
Protein Size: 1001

Molekulargewicht: 114 kDa

Gen-ID: 9810

NCBI Accession: NM_014771, NP_055586

UniProt: O75150