UBE3C Antikörper (N-Term)

Produktnummer ABIN2774719

Produktdetails anti-UBE3C Antikörper

Target: UBE3C (Ubiquitin Protein Ligase E3C (UBE3C))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE3C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MFSFEGDFKT RPKVSLGGAS RKYSIQRSAF DRCATLSQSG GAFPIANGPN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against UBE3C. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human UBE3C

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBE3C

Target: UBE3C (Ubiquitin Protein Ligase E3C (UBE3C))

Andere Bezeichnung: UBE3C (UBE3C Produkte)

Hintergrund: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. UBE3C can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. It has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Protein Interaction Partner: UBC, GOLGA2, PSMD14, SHFM1, UBE2D1, PSMD2, PSMC5, PANK4, EEF2K, WDR92, TLK1, MTA2, ECT2, CPEB4, THOC7, RBM15, THOC2, WDR74, KDM1A, USP13, UTRN, PHKA2, APP, UBE2L3, UBE3C, PSMA2, ELAVL1, RAD21, MYC, CAND2, PSMD6,
Protein Size: 404

Molekulargewicht: 44 kDa

Gen-ID: 9690