Der Kaninchen Polyklonal Anti-UBE3C-Antikörper wurde für WB validiert. Er ist geeignet, UBE3C in Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Hund zu detektieren.
UBE3C
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
UBE3C
(Ubiquitin Protein Ligase E3C (UBE3C))
Andere Bezeichnung
UBE3C
Hintergrund
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. UBE3C can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. It has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. Protein Interaction Partner: UBC, GOLGA2, PSMD14, SHFM1, UBE2D1, PSMD2, PSMC5, PANK4, EEF2K, WDR92, TLK1, MTA2, ECT2, CPEB4, THOC7, RBM15, THOC2, WDR74, KDM1A, USP13, UTRN, PHKA2, APP, UBE2L3, UBE3C, PSMA2, ELAVL1, RAD21, MYC, CAND2, PSMD6, Protein Size: 404