FBXO7 Antikörper (Middle Region)

Produktnummer ABIN2774701

Der Kaninchen Polyklonal Anti-FBXO7-Antikörper wurde für WB und IP validiert. Er ist geeignet, FBXO7 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd und Schwein zu detektieren.

Kurzübersicht für FBXO7 Antikörper (Middle Region) (ABIN2774701)

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-FBXO7 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PGETPSQFPP LRPRFDPVGP LPGPNPILPG RGGPNDRFPF RPSRGRPTDG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXO7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 522 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXO7

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Andere Bezeichnung: FBXO7

Hintergrund: FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
Alias Symbols: DKFZp686B08113, FBX, FBX07, FBX7, PKPS, PARK15
Protein Interaction Partner: PSME3, PSMF1, PSMA3, SKP1, TRAF2, MAGED1, SHFM1, PINK1, PARK2, SEC24C, NEDD8, UBC, COPS5, COPS6, CUL1, BIRC2, RBBP6, XPO1, DLGAP5, ELF4, BIRC3, CDK6, UBE2D2, CDC34,
Protein Size: 522

Molekulargewicht: 58 kDa

Gen-ID: 25793

NCBI Accession: NM_012179, NP_036311

UniProt: Q9Y3I1