FBXO5 Antikörper (C-Term)
Kurzübersicht für FBXO5 Antikörper (C-Term) (ABIN2774700)
Target
Alle FBXO5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- C-Term
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                                            Sequenz
- ASVQKSAAQT SLKKDAQTKL SNQGDQKGST YSRHNEFSEV AKTLKKNESL
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                                            Homologie
- Dog: 85%, Human: 100%, Pig: 79%, Rabbit: 92%
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                                            Produktmerkmale
- This is a rabbit polyclonal antibody against FBXO5. It was validated on Western Blot using a cell lysate as a positive control.
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                                            Aufreinigung
- Affinity Purified
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                                            Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human FBXO5
 
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                                            Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            Kommentare
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                        Antigen size: 447 AA 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Liquid
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                                            Konzentration
- Lot specific
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                                            Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Handhabung
- Avoid repeated freeze-thaw cycles.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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                                            : "Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles."    in: PLoS pathogens, Vol. 3, Issue 7, pp. e104, (2007)         (PubMed).        
 
 
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                                            : "Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles."    in: PLoS pathogens, Vol. 3, Issue 7, pp. e104, (2007)         (PubMed).        
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    - FBXO5 (F-Box Protein 5 (FBXO5))
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                                            Andere Bezeichnung
- FBXO5
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                                            Hintergrund
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                        FBXO5 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class and is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
 Alias Symbols: EMI1, FBX5, Fbxo31
 Protein Interaction Partner: FBXW11, UBE2S, SKP1, UBC, TPM3, NEDD8, BRCA1, BARD1, ANAPC1, ANAPC11, ANAPC7, ANAPC5, FZR1, ANAPC4, ANAPC2, CDC16, CDC23, CDC27, CDC20, CDK1, MYC, Gm9174, BTRC, PLK1, EVI5,
 Protein Size: 447
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                                            Molekulargewicht
- 50 kDa
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                                            Gen-ID
- 26271
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                                            NCBI Accession
- NM_012177, NP_036309
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                                            UniProt
- Q9UKT4
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                                            Pathways
- Mitotic G1-G1/S Phases
 Target
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