F-Box Protein 3 Antikörper (N-Term)

Produktnummer ABIN2774697

Dieses Anti-F-Box Protein 3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von F-Box Protein 3 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für F-Box Protein 3 Antikörper (N-Term) (ABIN2774697)

Target: F-Box Protein 3 (FBXO3)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F-Box Protein 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-F-Box Protein 3 Antikörper

Bindungsspezifität: N-Term

Sequenz: NCCYVSRRLS QLSSHDPLWR RHCKKYWLIS EEEKTQKNQC WKSLFIDTYS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXO3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 415 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu F-Box Protein 3

Target: F-Box Protein 3 (FBXO3)

Andere Bezeichnung: FBXO3

Hintergrund: FBXO3 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO3 belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end.
Alias Symbols: DKFZp564B092, FBA, FBX3
Protein Interaction Partner: DCP2, tat, UBC, HSP90AA1, UBD, HIPK2, COPS5, RBX1, CUL1, CUL3, SKP1, PML, NEDD8, EP300, TNFAIP3,
Protein Size: 415

Molekulargewicht: 47 kDa

Gen-ID: 26273

NCBI Accession: NM_033406, NP_208385

UniProt: Q9UK99