FBXL5 Antikörper (Middle Region)

Produktnummer ABIN2774689

Dieses Anti-FBXL5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FBXL5 in WB und IHC. Geeignet für Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Pferd und Schwein.

Kurzübersicht für FBXL5 Antikörper (Middle Region) (ABIN2774689)

Target: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FBXL5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: VHWARGDWYS GPATELDTEP DDEWVKNRKD ESRAFHEWDE DADIDESEES

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXL5. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXL5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 691 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXL5

Target: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Andere Bezeichnung: FBXL5

Hintergrund: FBXL5 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL5 belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: FBL4, FBL5, FLR1
Protein Interaction Partner: NABP2, CUL1, SNAI1, SKP1, FBXL5, HERC2, UBC, IREB2, ACO1, RBX1, MUS81, MMS19, FAM96B, ORC4, EP300, SMURF1, BTG1, COPS5, PLK1, CSNK2B, DCTN1,
Protein Size: 691

Molekulargewicht: 76 kDa

Gen-ID: 26234

NCBI Accession: NM_012161, NP_036293

UniProt: Q9UKA1

Pathways: Transition Metal Ion Homeostasis