FBXL2 Antikörper (N-Term)

Produktnummer ABIN2774686

Der Kaninchen Polyklonal Anti-FBXL2-Antikörper wurde für WB validiert. Er ist geeignet, FBXL2 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für FBXL2 Antikörper (N-Term) (ABIN2774686)

Target: FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXL2 Antikörper

Bindungsspezifität: N-Term

Sequenz: NISKRCGGFL RKLSLRGCIG VGDSSLKTFA QNCRNIEHLN LNGCTKITDS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 423 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXL2

Target: FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))

Andere Bezeichnung: FBXL2

Hintergrund: FBXL2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL2 belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats.
Alias Symbols: DKFZP564P0622, FBL2, FBL3
Protein Interaction Partner: SKP1, RABGGTB, PIK3R1, CDC34, CUL2, UBE2D3, PTPN13, PIK3R2, HSP90AA1, AURKB, HCVgp1, CCND2, CUL1, APP, COL7A1,
Protein Size: 423

Molekulargewicht: 47 kDa

Gen-ID: 25827

NCBI Accession: NM_012157, NP_036289

UniProt: Q9UKC9