Retinoid X Receptor beta Antikörper (N-Term)

Produktnummer ABIN2774660

Dieses Anti-Retinoid X Receptor beta-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Retinoid X Receptor beta in WB. Geeignet für Human, Maus, Ratte, Hund, Meerschweinchen und Rind (Kuh).

Kurzübersicht für Retinoid X Receptor beta Antikörper (N-Term) (ABIN2774660)

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoid X Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Retinoid X Receptor beta Antikörper

Bindungsspezifität: N-Term

Sequenz: GDSGRDSRSP DSSSPNPLPQ GVPPPSPPGP PLPPSTAPSL GGSGAPPPPP

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Schwein, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RXRB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RXRB

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-RXRB Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 533 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Andere Bezeichnung: RXR-beta / RXRB

Hintergrund: RXRB is a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DAUDI6, H-2RIIBP, MGC1831, NR2B2, RCoR-1
Protein Interaction Partner: NR1H3, RARB, UBC, PTMS, CACNA1B, SPOP, RARA, ZDHHC12, VDR, GRIP1, SRA1, MED1, Cebpb, SUMO2, NR1I2, NR1H2, NR2C2, THRB, SRC, RARG, PPARG, PPARD, NR4A2, MAP4, GTF2H1, NR3C1, TAF11, THRA, TACC2, AKAP13, NR0B2, NR2E3, NCOA1, NRIP1, NCOA3, RXRB,
Protein Size: 533

Molekulargewicht: 57 kDa

Gen-ID: 6257

NCBI Accession: NM_021976, NP_068811

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway