DMRT1 Antikörper (N-Term)

Produktnummer ABIN2774657

Der Kaninchen Polyklonal anti-DMRT1 Antikörper wird verwendet zum Nachweis von DMRT1 in Proben von Human, Rind (Kuh), Hund, Kaninchen und Schwein. Er wurde validiert für WB.

Kurzübersicht für DMRT1 Antikörper (N-Term) (ABIN2774657)

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Reaktivität: Human, Rind (Kuh), Hund, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMRT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DMRT1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: DMRT1 Antibody - N-terminal region

Sequenz: PNDEAFSKPS TPSEAPHAPG VPPQGRAGGF GKASGALVGA ASGSSAGGSS

Kreuzreaktivität: Rind (Kuh), Hund, Human, Schwein

Homologie: Cow: 78%, Dog: 85%, Human: 100%, Pig: 78%, Rabbit: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against DMRT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DMRT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DMRT1

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Andere Bezeichnung: DMRT1

Hintergrund:

Background Information: The gene encodes the DMRT1 protein is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. This suggested that DMRT1 may be required for testis development.This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Doublesex and mab-3 related transcription factor 1

Alternative Symbols: DMT1, CT154

Protein Name: Doublesex- and mab-3-related transcription factor 1

Molekulargewicht: 39kDa

Gen-ID: 1761

NCBI Accession: NP_068770

UniProt: Q9Y5R6