NEFM Antikörper (C-Term)

Produktnummer ABIN2774450

Dieses Anti-NEFM-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NEFM in WB. Geeignet für Human, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd und Schaf.

Kurzübersicht für NEFM Antikörper (C-Term) (ABIN2774450)

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Reaktivität: Human, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEFM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NEFM Antikörper

Bindungsspezifität: C-Term

Sequenz: EVEGKEEVEQ ETKEKGSGRE EEKGVVTNGL DLSPADEKKG GDKSEEKVVV

Homologie: Cow: 93%, Dog: 86%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against NEFM. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NEFM

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 540 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NEFM

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Andere Bezeichnung: NEFM

Hintergrund: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: NEF3, NF-M, NFM
Protein Interaction Partner: SART3, PARK2, RB1, SMAD2, FOS, IQCB1, SIRT7, UBC, DISC1, TNIK, SQSTM1, MINK1, STXBP1, NEFH, APOE,
Protein Size: 540

Molekulargewicht: 59 kDa

Gen-ID: 4741

NCBI Accession: NM_001105541, NP_001099011

UniProt: E9PBF7

Pathways: Brown Fat Cell Differentiation