BDKRB1 Antikörper (C-Term)

Produktnummer ABIN2774418

Der Kaninchen Polyklonal Anti-BDKRB1-Antikörper wurde für WB validiert. Er ist geeignet, BDKRB1 in Proben von Human, Ratte, Maus und Schwein zu detektieren.

Kurzübersicht für BDKRB1 Antikörper (C-Term) (ABIN2774418)

Target: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Reaktivität: Human, Ratte, Maus, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BDKRB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BDKRB1 Antikörper

Bindungsspezifität: C-Term

Sequenz: RTREEVSRTR CGGRKDSKTT ALILTLVVAF LVCWAPYHFF AFLEFLFQVQ

Homologie: Human: 100%, Mouse: 92%, Pig: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against BDKRB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human BDKRB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 353 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BDKRB1

Target: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Andere Bezeichnung: BDKRB1

Hintergrund: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: B1BKR, B1R, BKB1R, BKR1, BRADYB1
Protein Interaction Partner: GNAQ, MEP1A,
Protein Size: 353

Molekulargewicht: 40 kDa

Gen-ID: 623

NCBI Accession: NM_000710, NP_000701

UniProt: P46663

Pathways: ACE Inhibitor Pathway