PDIA3 Antikörper (C-Term)

Produktnummer ABIN2774375

Der Kaninchen Polyklonal Anti-PDIA3-Antikörper wurde für WB, IHC und IP validiert. Er ist geeignet, PDIA3 in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Kaninchen, Pferd, Ziege, Schaf und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für PDIA3 Antikörper (C-Term) (ABIN2774375)

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Kaninchen, Pferd, Ziege, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDIA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-PDIA3 Antikörper

Bindungsspezifität: C-Term

Sequenz: YFSPANKKLN PKKYEGGREL SDFISYLQRE ATNPPVIQEE KPKKKKKAQE

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PDIA3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 505 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDIA3

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Andere Bezeichnung: PDIA3

Hintergrund: This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Alias Symbols: ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC
Protein Interaction Partner: FUS, UBC, MDM2, SUZ12, ABCE1, RBBP4, RAB1A, PGD, MTAP, MTPN, BCCIP, CNDP2, NANS, DAK, ACOT7, NPEPPS, SLC9A3R1, RPL23, SMS, LDHA, HSPD1, CSE1L, ATP6V1A, ADSS, EGFR, UBD, CANX, CALR, HDAC10, MTOR, EFEMP1, ATF2, COL6A1, CLU, APP, ADAM10, AGRN, DCBLD1, RICTOR
Protein Size: 505

Molekulargewicht: 56 kDa

Gen-ID: 2923

NCBI Accession: NM_005313, NP_005304

UniProt: P30101

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis