CD1b Antikörper (N-Term)

Produktnummer ABIN2774371

Der Kaninchen Polyklonal anti-CD1b Antikörper wird verwendet zum Nachweis von CD1b in Proben von Human, Meerschweinchen, Rind (Kuh), Hund, Pferd und Schaf. Er wurde validiert für WB.

Kurzübersicht für CD1b Antikörper (N-Term) (ABIN2774371)

Target: CD1b (CD1B)

Reaktivität: Human, Meerschweinchen, Rind (Kuh), Hund, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD1b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD1b Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CD1B Antibody - N-terminal region

Sequenz: TAIFLKPWSK GNFSDKEVAE LEEIFRVYIF GFAREVQDFA GDFQMKYPFE

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CD1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63421-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CD1b

Target: CD1b (CD1B)

Andere Bezeichnung: CD1B

Hintergrund:

Background Information: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

Gene Name: CD1b molecule

Alternative Symbols: R1, CD1, CD1A

Protein Name: T-cell surface glycoprotein CD1b

Molekulargewicht: 37kDa

Gen-ID: 910

NCBI Accession: NP_001755

UniProt: P29016