CD1b Antikörper (N-Term)
Kurzübersicht für CD1b Antikörper (N-Term) (ABIN2774371)
Target
Alle CD1b (CD1B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- TAIFLKPWSK GNFSDKEVAE LEEIFRVYIF GFAREVQDFA GDFQMKYPFE
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Homologie
- Cow: 86%, Dog: 79%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Sheep: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CD1B. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 333 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD1b (CD1B)
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Andere Bezeichnung
- CD1B
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Hintergrund
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This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Alias Symbols: CD1, CD1A, MGC125990, MGC125991, R1
Protein Interaction Partner: UBC, PSAP, B2M,
Protein Size: 333 -
Molekulargewicht
- 37 kDa
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Gen-ID
- 910
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NCBI Accession
- NM_001764, NP_001755
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UniProt
- P29016
Target
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