MRPS18B Antikörper (N-Term)

Produktnummer ABIN2774354

Produktdetails anti-MRPS18B Antikörper

Target: MRPS18B (Mitochondrial Ribosomal Protein S18B (MRPS18B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPS18B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SVPISPYKDE PWKYLESEEY QERYGSRPVW ADYRRNHKGG VPPQRTRKTC

Homologie: Cow: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against MRPS18B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 258 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MRPS18B

Target: MRPS18B (Mitochondrial Ribosomal Protein S18B (MRPS18B))

Andere Bezeichnung: MRPS18B (MRPS18B Produkte)

Synonyme: Ptd017 antikoerper, C6orf14 antikoerper, HSPC183 antikoerper, HumanS18a antikoerper, MRP-S18-2 antikoerper, MRPS18-2 antikoerper, PTD017 antikoerper, S18amt antikoerper, 2400002C15Rik antikoerper, mitochondrial ribosomal protein S18B antikoerper, Mrps18b antikoerper, MRPS18B antikoerper

Hintergrund: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins.
Alias Symbols: C6orf14, DKFZp564H0223, HSPC183, HumanS18a, MRP-S18-2, MRPS18-2, PTD017, S18amt
Protein Interaction Partner: TUBGCP4, CEP250, TUBGCP3, VCP, TP53, NEDD1, UBC, PARK2, EXOSC6, EWSR1, mug82, ICT1, EBNA3B, RB1, MRPS9, MRPS26, MRPS25, MRPS35, MRPS22, UBR5, MRPS28, QARS, MYH9, KARS, HNRNPAB, FUS, CAND1, CUL3, Ybx1, NFKBIL1,
Protein Size: 258

Molekulargewicht: 28 kDa

Gen-ID: 28973

NCBI Accession: NM_014046, NP_054765

UniProt: Q9Y676