CFHR1 Antikörper (N-Term)

Produktnummer ABIN2774339

Der Kaninchen Polyklonal Anti-CFHR1-Antikörper wurde für WB validiert. Er ist geeignet, CFHR1 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für CFHR1 Antikörper (N-Term) (ABIN2774339)

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CFHR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CFHR1 Antikörper

Bindungsspezifität: N-Term

Sequenz: NHGILYDEEK YKPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCTEEGWS

Homologie: Human: 100%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against CFHR1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 330 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CFHR1

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Andere Bezeichnung: CFHR1

Hintergrund: This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Alias Symbols: CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2, MGC104329
Protein Interaction Partner: PRDX4, LBP, APOA1, CFH,
Protein Size: 330

Molekulargewicht: 36 kDa

Gen-ID: 3078

NCBI Accession: NM_002113, NP_002104

UniProt: Q03591