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EIF6 Antikörper (N-Term)

This anti-EIF6 antibody (ABIN2774313) is a Rabbit Polyclonal antibody detecting EIF6 in WB. Suitable for Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Sheep, Saccharomyces cerevisiae, Zebrafish (Danio rerio).
Produktnummer ABIN2774313

Kurzübersicht für EIF6 Antikörper (N-Term) (ABIN2774313)

Target

Alle EIF6 Antikörper anzeigen
EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Reaktivität

  • 37
  • 20
  • 19
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt

  • 34
  • 3
Kaninchen

Klonalität

  • 35
  • 2
Polyklonal

Konjugat

  • 26
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser EIF6 Antikörper ist unkonjugiert

Applikation

  • 24
  • 14
  • 9
  • 6
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    AVRASFENNC EIGCFAKLTN TYCLVAIGGS ENFYSVFEGE LSDTIPVVHA

    Homologie

    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Yeast: 85%, Zebrafish: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against EIF6. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 245 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

    Andere Bezeichnung

    EIF6

    Hintergrund

    Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits.
    Alias Symbols: 2, CAB, EIF3A, ITGB4BP, b, b(2)gcn, gcn, p27BBP, eIF-6, p27(BBP)
    Protein Interaction Partner: ZNF622, BCCIP, PPAN, NMD3, GLTSCR2, GTPBP4, POP1, TOP2B, TOP2A, RNF2, CNBP, RARS, PPP5C, PEPD, PAFAH1B2, HSPA9, HSPA1A, HPRT1, EIF4E, DFFA, CFL1, CAPN1, ASNA1, GINS3, BZW2, ABHD14A, TNFAIP8, XRN2, HDAC9, ZBTB26, VCAM1, UBC, ECT2, HNRNPU, FBL, DHX9, APP, R
    Protein Size: 245

    Molekulargewicht

    27 kDa

    Gen-ID

    3692

    NCBI Accession

    NM_002212, NP_002203

    UniProt

    P56537

    Pathways

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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