MAP3K10 Antikörper (C-Term)

Produktnummer ABIN2774283

Der Kaninchen Polyklonal Anti-MAP3K10-Antikörper wurde für WB validiert. Er ist geeignet, MAP3K10 in Proben von Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen und Schwein zu detektieren.

Kurzübersicht für MAP3K10 Antikörper (C-Term) (ABIN2774283)

Target: MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAP3K10 Antikörper

Bindungsspezifität: C-Term

Sequenz: TLTFAPRPRP AASRPRLDPW KLVSFGRTLT ISPPSRPDTP ESPGPPSVQP

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAP3K10. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAP3K10

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 954 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAP3K10

Target: MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))

Andere Bezeichnung: MAP3K10

Hintergrund: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Alias Symbols: MEKK10, MLK2, MST
Protein Interaction Partner: MAPK9, MAPK1, MAP3K10, MAPK14, GARS, COPS2, KIAA1804, ABL2, SH3RF1, CNKSR1, YWHAE, RACGAP1, KIF3A, DNM1L, KIF3B, DLG4, KIFAP3, MAP2K4, TUBB, PHB, HTT, CLTC, CDC42, CEACAM1, HGS, DNM1, KRTAP3-4P, KIF17, MAPK8IP2, MAPK8IP1, RAC1, HPCA, NEUROD1,
Protein Size: 954

Molekulargewicht: 104 kDa

Gen-ID: 4294

NCBI Accession: NM_002446, NP_002437

UniProt: Q02779