GAN Antikörper (Middle Region)

Produktnummer ABIN2774225

Produktdetails anti-GAN Antikörper

Target: GAN (Gigaxonin (GAN))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IYLNDQNLCI PASSSFVYGA VPIGASIYVI GDLDTGTNYD YVREFKRSTG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GAN. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GAN

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 597 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GAN

Target: GAN (Gigaxonin (GAN))

Andere Bezeichnung: GAN (GAN Produkte)

Synonyme: MGC81691 antikoerper, GAN antikoerper, A330045G18 antikoerper, gigaxonin antikoerper, GAN1 antikoerper, KLHL16 antikoerper, gigaxonin L homeolog antikoerper, gigaxonin antikoerper, giant axonal neuropathy antikoerper, gan.L antikoerper, gan antikoerper, GAN antikoerper, Gan antikoerper

Hintergrund: This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN).
Alias Symbols: FLJ38059, GAN1, KLHL16
Protein Interaction Partner: RELA, HSP90AA1, CUL3, UBA1, TBCB, UBC, ATG16L1, RBX1, MAP1B, SFN,
Protein Size: 597

Molekulargewicht: 66 kDa

Gen-ID: 8139

NCBI Accession: NM_022041, NP_071324

UniProt: Q9H2C0