RNF216 Antikörper (N-Term)

Produktnummer ABIN2774202

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RNF216 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für RNF216 Antikörper (N-Term) (ABIN2774202)

Target: RNF216 (Ring Finger Protein 216 (RNF216))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF216 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RNF216 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Rnf216 Antibody - N-terminal region

Sequenz: IVNPRLEQKV IILGENGLLF PESEPLEVQN QSSEDSETEL LSNPGEPAAS

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Rnf216. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Rnf216

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57824-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RNF216

Target: RNF216 (Ring Finger Protein 216 (RNF216))

Andere Bezeichnung: Rnf216

Hintergrund:

Background Information: Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis.

Gene Name: ring finger protein 216

Alternative Symbols: UIP, UIP83, C86502, TRIAD3, Ubce7i, AI647468, AU019462, Ubce7ip1, 2810055G22Rik, F830018F18Rik

Protein Name: E3 ubiquitin-protein ligase RNF216

Molekulargewicht: 93kDa

Gen-ID: 108086

UniProt: P58283